Population
in vitro model of messenger RNA precursor splicing (adenovirus 2 major late transcript)
Design
Preclinical
Authors
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No immediate clinical impact; leaves open branchpoint targeting for splicing modulation research.
This basic science study characterizes the lariat RNA structure as an intermediate in mRNA splicing.
Padgett et al. (1984) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: