Key result
CV risk factor differences explain sex gaps in CHD, with aging driving greater risk in women.
Why the study?
Differences in major cardiovascular risk factors contributing to sex differences in CHD risk and their association with age-related CHD incidence and mortality were not fully understood.
Major cardiovascular risk factors explain a substantial portion of sex differences in CHD risk, and age-related increases in these factors disproportionately impact CHD incidence and mortality in women.
May warrant closer risk factor monitoring in aging women; leaves open whether sex-specific interventions alter CHD trajectories.
Differences in major cardiovascular risk factors explained a substantial part of the sex difference in CHD risk. An increase in risk factor levels was associated with the age-related increase in CHD incidence and mortality in both sexes but to a larger extent in women.
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Jousilahti et al. (1999) studied this question. Differences in major cardiovascular risk factors explained a substantial part of the sex difference in CHD risk, with age-related increases driving CHD incidence and mortality more strongly in women.
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