Genotype determination of hepatitis C virus from Northern India: Identification of a new subtype

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Population

11 Hepatitis C virus (HCV) isolates from India

Design

Other

Authors

Discussion

Alerts clinicians to emerging HCV variants in India; leaves open implications for diagnostics and subtype-specific outcomes.

Population

11 Hepatitis C virus (HCV) isolates from India

Intervention

Genotyping using sequence comparison for part of the non-structural (NS5) and structural (core) regions via RT-PCR, cloning, and sequencing

Outcome

HCV genotype classification based on phylogenetic analysis

Identified a new HCV subtype (3g) and demonstrated that type 3 variants are a major cause of HCV infection in India.

Panigrahi et al. (1996) studied this question.

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