Key result
New age- and sex-specific carotid IMT percentiles enable standardized cardiovascular risk assessment across populations.
Why the study?
Age- and sex-specific reference percentiles for common carotid intima-media thickness and their relation with cardiovascular risk factors were not established in a healthy population.
Provides age- and sex-specific reference intervals for CCIMT measured by echotracking to aid in interpreting IMT values across different cardiovascular risk profiles.
May aid IMT interpretation in varied risk groups; leaves open prognostic validation in prospective cohorts.
We estimated age- and sex-specific percentiles of CCIMT in a healthy population and assessed the association of CV-RFs with CCIMT Z-scores, which enables comparison of IMT values for (patient) groups with different cardiovascular risk profiles, helping interpretation of such measures obtained both in research and clinical settings.
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Engelen et al. (2012) studied this question. Age- and sex-specific percentiles for common carotid intima-media thickness were established to enable standardized comparisons of IMT values across different cardiovascular risk profiles.
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