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December 1, 1986Circulation

Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging.

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Why the study?

Does B-mode real-time ultrasound imaging accurately measure intimal + medial thickness in human arteries compared to pathologic examination?

Population

In vitro specimens of human aortic and common carotid arteries, and 10 young normal male subjects.

Comparison

B-mode real-time ultrasound imaging for direct… vs Pathologic examination

Design

Other

Authors

PPP PignoliTecnologie Avanzate (Italy)ETElena TremoliPreventive CardiologyAPAndrea PoliMercatorum University

Discussion

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Implication

In vitro agreement supports B-mode IMT feasibility; leaves open in vivo validation and clinical translation.

Structured PICO

Does B-mode real-time ultrasound imaging accurately measure intimal + medial thickness in human arteries compared to pathologic examination?

P
Population
In vitro specimens of human aortic and common carotid arteries (classified as relatively normal or with atherosclerotic plaques), and 10 young normal male subjects (in vivo).
I
Intervention
B-mode real-time ultrasound imaging for direct measurement of intimal + medial thickness
C
Comparator
Pathologic examination (gross and microscopic evaluation)
O
Outcome
Accuracy and correlation of intimal + medial thickness measured by B-mode imaging compared to pathologic examinationsurrogate

B-mode ultrasound imaging is a feasible and accurate non-invasive method for directly measuring the intimal-medial thickness of human arteries in vivo.

Cite This Study

Pignoli et al. (1986) studied this question.

synapsesocial.com/papers/69dd358b7808b00a4799b70ehttps://doi.org/10.1161/01.cir.74.6.1399
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Use of Ultrasonic Spectroscopy to Characterize Calcified Lesions1981 · 6 citations
  2. 2Velocity and attenuation of sound in arterial tissues1982 · 36 citations
  3. 3In Vivo Measurement of Thickness or of Speed of Sound in Biological Tissue Structures1983 · 9 citations