Baseline Values but Not Treatment-Induced Changes in Carotid Intima-Media Thickness Predict Incident Cardiovascular Events in Treated Hypertensive Patients
Why the study?
Do baseline values and treatment-induced changes in carotid intima-media thickness predict incident cardiovascular events in treated hypertensive patients?
Population
Treated hypertensive patients
Design
Cohort
Authors
Discussion
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Member takes
Implication
Baseline carotid IMT assessment may refine risk stratification in treated hypertension; leaves open whether serial IMT changes add prognostic value.
Structured PICO
Do baseline values and treatment-induced changes in carotid intima-media thickness predict incident cardiovascular events in treated hypertensive patients?
P
Population
Treated hypertensive patients
I
Intervention
Baseline carotid intima-media thickness (IMT) and treatment-induced IMT changes
O
Outcome
Incident cardiovascular eventshard clinical
Baseline carotid intima-media thickness and plaques, but not treatment-induced changes, independently predict incident cardiovascular events in treated hypertensive patients.
Limitations
- Smallness of treatment-dependent IMT changes compared with the large individual differences in baseline IMTs
Cite This Study
Zanchetti et al. (2009) studied this question.