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March 7, 2019PLoS ONEOpen Access

Comparison of triglyceride glucose index, and related parameters to predict insulin resistance in Korean adults: An analysis of the 2007-2010 Korean National Health and Nutrition Examination Survey

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Why the study?

Studies evaluating the efficiency of markers combining the TyG index with obesity markers to reflect insulin resistance were limited in number and had inconsistent results.

Which combination of triglyceride glucose (TyG) index and obesity indices best predicts insulin resistance in Korean adults?

Population

11,149 subjects (4,777 men and 6,372 women) from the Korean National Health and Nutrition Examination Survey

Comparison

TyG index, TyG-BMI, TyG-WC, and TyG-WHtR

Design

Cross-sectional survey analysis

Authors

JLJinsook LimChungnam National University HospitalJKJimyung KimChungnam National UniversitySKSun Hoe KooChangi General Hospital

Discussion

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Implication

TyG-BMI may aid IR prediction in Koreans; hypothesis-generating and requires prospective validation before clinical adoption.

Structured PICO

Which combination of triglyceride glucose (TyG) index and obesity indices best predicts insulin resistance in Korean adults?

P
Population
11,149 Korean adults (4,777 men and 6,372 women) from the 2007-2010 Korean National Health and Nutrition Examination Survey
I
Intervention
Triglyceride glucose (TyG) index and obesity indices combinations (TyG-BMI, TyG-WC, TyG-WHtR)
C
Comparator
Quartile 1 of each parameter as reference, and comparison between parameters
O
Outcome
Insulin resistance (defined as HOMA-IR above the 75th percentile for each gender)surrogate

TyG-BMI is superior to TyG index alone or other TyG-obesity combinations for predicting insulin resistance in Korean adults.

Cite This Study

Lim et al. (2019) studied this question.

synapsesocial.com/papers/69dd39480a7b4bc8c4100fbdhttps://doi.org/10.1371/journal.pone.0212963
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