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Hydrolytic enzymes and microorganisms were employed in enantioselective syntheses of bioregulators such as hormones and pheromones. Esterases and lipases were useful in achieving optical resolution, conversion of meso-compounds to optically active compounds, and macrolactonization. Yeasts provided a variety of optically active hydroxy ketones and esters, which served as versatile non-racemic chiral building blocks.
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Kenji Mori (1995) studied this question.
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