What question did this study set out to answer?

Determine how complexation with borate ions alters the electrophoretic mobility and separation efficiency of carbohydrates during capillary electrophoresis.

August 1, 1991Analytical Chemistry

Influence of borate complexation on the electrophoretic behavior of carbohydrates in capillary electrophoresis

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Authors

SHSabrina Hoffstetter‐KuhnInstitut Für Angewandte Kulturforschung APAran PaulusBoston University EGErnst GassmannNovartis (Switzerland)

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Implication

Analytical chemistry investigation demonstrates borate complexation of neutral carbohydrates, indicating improved electrophoretic resolution and separation.

Key Points

Determine how complexation with borate ions alters the electrophoretic mobility and separation efficiency of carbohydrates during capillary electrophoresis.
Applied capillary electrophoresis to analyze carbohydrates using alkaline borate running buffers.
Assessed changes in migration times and electrophoretic mobility based on borate-sugar complex formation.
Borate ions react with hydroxyl groups on neutral carbohydrates to form negatively charged complexes, enabling electrophoretic migration.
Separation efficiency and migration order depend directly on carbohydrate stereochemistry and borate electrolyte concentration.

Cite This Study

Hoffstetter‐Kuhn et al. (1991) studied this question.

synapsesocial.com/papers/69dd3e7bfb7610310c101393 https://doi.org/10.1021/ac00015a009

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Implication

Analytical chemistry investigation demonstrates borate complexation of neutral carbohydrates, indicating improved electrophoretic resolution and separation.

Influence of borate complexation on the electrophoretic behavior of carbohydrates in capillary electrophoresis

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Member takes

Implication

Key Points

Cite This Study

Influence of borate complexation on the electrophoretic behavior of carbohydrates in capillary electrophoresis

Discussion

Member takes

Implication

Key Points

Cite This Study

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