What question did this study set out to answer?

Provide historical context for dietary supplement regulation and science, review existing research infrastructure, and outline future directions for clinical evaluation and technological integration.

July 4, 2024Civil War Book ReviewOpen Access

The Evolution of Science and Regulation of Dietary Supplements: Past, Present, and Future

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Authors

PCPaul M. CoatesUniversity of Salford RBRegan L BaileyFlorida State University JBJeffrey B. BlumbergTufts University

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Implication

Narrative review reveals evolving scientific methodologies and regulatory frameworks for dietary supplements in the United States, highlighting emerging roles for AI and personalized nutrition.

Key Points

Provide historical context for dietary supplement regulation and science, review existing research infrastructure, and outline future directions for clinical evaluation and technological integration.
Narrative synthesis tracing US regulatory developments since 1994 and the parallel evolution of supplement science.
Evaluation of evidentiary standards, clinical trial challenges, and the integration of emerging data science technologies into nutritional assessment.
Mechanistic understanding of dietary bioactive compounds has expanded substantially, but randomized clinical trials demonstrating definitive clinical endpoints remain scarce.
Emerging platforms including nutrigenomics, microbiome characterization, artificial intelligence, and machine learning are increasingly necessary to handle complex multi-ingredient products and support personalized clinical nutrition.

Cite This Study

Coates et al. (2024) studied this question.

synapsesocial.com/papers/69dd3ed7caee84831440c421 https://doi.org/10.1016/j.tjnut.2024.06.017

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Implication

Narrative review reveals evolving scientific methodologies and regulatory frameworks for dietary supplements in the United States, highlighting emerging roles for AI and personalized nutrition.

The Evolution of Science and Regulation of Dietary Supplements: Past, Present, and Future

Discussion

Member takes

Implication

Key Points

Cite This Study

The Evolution of Science and Regulation of Dietary Supplements: Past, Present, and Future

Discussion

Member takes

Implication

Key Points

Cite This Study

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