What question did this study set out to answer?

To review the epidemiological and clinical challenges associated with measuring the true morbidity and mortality burden of influenza virus infections.

February 5, 2018Current Epidemiology ReportsOpen Access

The Burden of Influenza: a Complex Problem

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To review the epidemiological and clinical challenges associated with measuring the true morbidity and mortality burden of influenza virus infections.
Narrative epidemiological review evaluating the clinical impacts of seasonal influenza A and B epidemics and historical pandemics.
Synthesis of diagnostic hurdles, indirect health sequelae, and secondary bacterial infections complicating attribution of outcomes to influenza.
A substantial portion of influenza-related severe morbidity and death arises from secondary bacterial superinfections and exacerbations of chronic conditions, such as congestive heart failure and myocardial infarction.
Complications frequently occur after the virus is no longer detectable, making causal attribution to influenza difficult in clinical and epidemiological surveillance.
Burden estimation is systematically constrained by limited access to sensitive diagnostics, unpredictable epidemic timelines, and the high cost of cohort studies.

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Implication

Review reveals difficulties in measuring influenza-associated morbidity and mortality across vulnerable populations, suggesting that true disease burden is significantly underestimated.

Cite This Study

Gordon et al. (2018) studied this question.

synapsesocial.com/papers/69dd40388557d5ab8f40c558 https://doi.org/10.1007/s40471-018-0136-1

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Implication

Review reveals difficulties in measuring influenza-associated morbidity and mortality across vulnerable populations, suggesting that true disease burden is significantly underestimated.

The Burden of Influenza: a Complex Problem

Key Points

Discussion

Implication

Cite This Study

The Burden of Influenza: a Complex Problem

Key Points

Discussion

Implication

Cite This Study

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