February 10, 2004Journal of Applied Physiology

Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery

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Why the study?

Does stent design (strut number, width, thickness) and deployment ratio influence wall shear stress in a computational model of a normal artery?

Population

Computational fluid dynamics models based on canine coronary artery diameter measurements.

Comparison

Stent designs with varying strut properties and… vs Comparisons between different strut numbers…

Design

Preclinical

Authors

JLJohn F. LaDisaMarquette University LOLars E. OlsonMarquette University İGİsmail GülerGazi University

Discussion

Member takes

Implication

Stent design optimization merits prospective trials; leaves open effects on clinical restenosis and should not yet guide practice.

Structured PICO

Does stent design (strut number, width, thickness) and deployment ratio influence wall shear stress in a computational model of a normal artery?

Population

Computational fluid dynamics models based on canine coronary artery diameter measurements.

Intervention

Stent designs with varying strut properties (4 or 8 struts; 0.197 or 0.329 mm width; 0.096 or 0.056 mm thickness) and deployment ratios (1.1:1 or 1.2:1) subjected to an inlet velocity of 0.105 m/s.

Comparator

Comparisons between different strut numbers, widths, thicknesses, and deployment ratios.

Outcome

Wall shear stress (WSS) and spatial WSS gradients expressed as a percentage of the stent and vessel area.surrogate

Computational modeling indicates that stent designs with fewer, thinner struts and lower deployment ratios reduce the area of low wall shear stress, potentially lowering the risk of neointimal hyperplasia.

Cite This Study

LaDisa et al. (2004) studied this question.

synapsesocial.com/papers/69dd40e2ac7bdbc6c71013a4 https://doi.org/10.1152/japplphysiol.01329.2003

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Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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