Why the study?
Is rheumatoid arthritis disease severity associated with increased coronary artery calcification compared to a general population cohort?
Is rheumatoid arthritis disease severity associated with increased coronary artery calcification compared to a general population cohort?
Rheumatoid arthritis severity is associated with increased coronary calcification, highlighting the need for cardiovascular prevention especially in men and younger patients with RA.
May warrant closer CV monitoring in severe RA; leaves open whether disease control alters calcification progression.
Increasing rheumatoid arthritis disease severity was associated with a higher prevalence and greater extent of coronary artery calcification, potentially mediated through an atherogenic effect of chronic systemic inflammation. Gender and age differences in association with coronary calcification suggest that preventive measures should be emphasized in men with rheumatoid arthritis, and considered even in younger rheumatoid arthritis patients with low levels of traditional cardiovascular risk factors.
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Giles et al. (2009) studied this question.
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