Why the study?
Does alpha-lipoic acid ameliorate cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy?
Population
Experimental diabetic cardiomyopathy model
Design
Preclinical
Authors
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Hypothesis-generating in experimental diabetic cardiomyopathy; leaves open translation to human cardiac fibrosis therapy.
Does alpha-lipoic acid ameliorate cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy?
Alpha-lipoic acid demonstrates therapeutic potential for diabetic cardiomyopathy by ameliorating cardiac fibrosis and dysfunction in an experimental model.
Li et al. (2012) studied this question.
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