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March 1, 1999Journal of Biological ChemistryOpen Access

Regulation of the Hypoxia-inducible Transcription Factor 1α by the Ubiquitin-Proteasome Pathway

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PKPekka KallioTurku Centre for Computer ScienceWWW.J. WilsonLyell McEwin HospitalSOSallyann L. O’BrienO'Brien Institute

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Kallio et al. (1999) studied this question.

synapsesocial.com/papers/69dd4b450644c7b49d40cb3dhttps://doi.org/10.1074/jbc.274.10.6519
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transactivation and Inhibitory Domains of Hypoxia-inducible Factor 1α1997 · 621 citations
  2. 2Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation1997 · 383 citations
  3. 3Regulation of hypoxia-inducible factor 1α is mediated by an O <sub>2</sub> -dependent degradation domain via the ubiquitin-proteasome pathway1998 · 2,116 citations