Why the study?
Spontaneous coronary artery dissection remains a persistent clinical challenge with dismal outcomes, underdiagnosis, and largely supportive management with controversial intervention roles.
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This review summarizes current knowledge on spontaneous coronary artery dissection, highlighting its increasing prevalence, diagnostic challenges, disproportionate effect on women, and the need for further research given its largely supportive management.
The prevalence of spontaneous coronary artery dissection (SCAD) has increased over the last decades in young adults presenting with acute coronary syndrome. Although the diagnostic tools, including intracoronary imaging, have permitted a more accurate diagnosis of SCAD, the prognosis and overall outcomes remain dismal. Furthermore, the disproportionate sex distribution affecting more women and the underdiagnosis in many parts of the world render this pathology a persistent clinical challenge, particularly since the management remains largely supportive with a limited and controversial role for percutaneous or surgical interventions. The purpose of this review is to summarize the available literature on SCAD and to provide insights into the gaps in knowledge and areas requiring further investigation.
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Kaddoura et al. (2023) studied this question.
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