Key result
SCAD remains an important cause of MI in younger women despite uncertain diagnosis and management.
Why the study?
Ongoing challenges remain in diagnosing SCAD and improving outcomes, with uncertainty surrounding optimal management, risk stratification, physical activity, reproductive planning, and genetic evaluations.
Prompts heightened awareness of SCAD in young women with MI; leaves open optimal diagnosis and management pending dedicated trials.
Over the past decade, spontaneous coronary artery dissection (SCAD) has emerged as an important cause of myocardial infarction, particularly among younger women. The pace of knowledge acquisition has been rapid, but ongoing challenges include accurately diagnosing SCAD and improving outcomes. Many SCAD patients experience substantial post-SCAD symptoms, recurrent SCAD, and psychosocial distress. Considerable uncertainty remains about optimal management of associated conditions, risk stratification and prevention of complications, recommendations for physical activity, reproductive planning, and the role of genetic evaluations. This review provides a clinical update on the diagnosis and management of patients with SCAD, including pregnancy-associated SCAD and pregnancy after SCAD, and highlight high-priority knowledge gaps that must be addressed.
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Hayes et al. (2020) conducted a review in Spontaneous coronary artery dissection (SCAD). Spontaneous coronary artery dissection is an important cause of myocardial infarction in younger women, but significant uncertainty remains regarding its optimal diagnosis and management.
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