Left ventricular pressure-volume and Frank-Starling relations in endurance athletes. Implications for orthostatic tolerance and exercise performance.
Why the study?
Do endurance athletes have altered left ventricular pressure-volume relations compared to nonathletes?
Population
Endurance athletes and nonathletes
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May explain orthostatic intolerance via Starling mechanics in athletes; leaves open causal effects of training on ventricular compliance.
Structured PICO
Do endurance athletes have altered left ventricular pressure-volume relations compared to nonathletes?
P
Population
Endurance athletes and nonathletes
C
Comparator
Nonathletes
O
Outcome
Left ventricular pressure-volume and Frank-Starling relations (ventricular diastolic chamber compliance and distensibility)surrogate
The increased ventricular compliance in endurance athletes places them on the steep portion of the Starling curve, potentially providing a mechanical, nonautonomic explanation for orthostatic intolerance.
Cite This Study
Levine et al. (1991) studied this question.