February 26, 2007Circulation
Drug-Eluting Stent and Coronary Thrombosis
Why the study?
Do drug-eluting stents increase the risk of stent thrombosis compared to bare-metal stents?
Population
Patients undergoing coronary stent implantation
Comparison
Drug-eluting stents (DES) vs Bare-metal stents (BMS)
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
Does not yet alter DES selection or DAPT duration; leaves open clinical translation of prothrombotic mechanisms.
Structured PICO
Do drug-eluting stents increase the risk of stent thrombosis compared to bare-metal stents?
P
Population
Patients undergoing coronary stent implantation
I
Intervention
Drug-eluting stents (DES)
C
Comparator
Bare-metal stents (BMS)
O
Outcome
Stent thrombosissafety
This review highlights the pathophysiological mechanisms by which drug-eluting stents may promote late stent thrombosis through delayed arterial healing and endothelial dysfunction.
Cite This Study
Lüscher et al. (2007) studied this question.