Why the study?
The vagus nerve modulates numerous bodily functions, generating broad interest across disciplines into its mechanistic basis and clinical efficacy.
This review summarizes current preclinical and clinical evidence on the efficacy and mechanistic basis of vagus nerve stimulation across various diseases.
Synthesizes vagus nerve stimulation evidence; leaves open its clinical role pending rigorous trials.
The vagus nerve, the great wanderer, is involved in numerous processes throughout the body and vagus nerve stimulation (VNS) has the potential to modulate many of these functions. This wide-reaching capability has generated much interest across a range of disciplines resulting in several clinical trials and studies into the mechanistic basis of VNS. This review discusses current preclinical and clinical evidence supporting the efficacy of VNS in different diseases and highlights recent advancements. Studies that provide insights into the mechanism of VNS are considered.
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Goggins et al. (2022) studied this question.
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