Does the CHA2DS2-VASc score identify patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy?
The CHA2DS2-VASc score can identify a subset of AF patients with a CHADS2 score of 1 who have a low enough stroke risk (1% annually) to potentially withhold oral anticoagulation.
The CHA(2)DS(2)-VASc score reclassifies 26% of patients with a CHADS(2) score of 1 to a low annual risk of SSE of 1%. This risk seems low enough to consider withholding anticoagulant treatment.
Coppens et al. (2012) studied this question.