Why the study?
Does maintaining aortic diastolic blood pressure above 30 mm Hg with epinephrine and saline improve successful resuscitation in a canine model of prolonged ventricular fibrillation?
Population
12 dogs undergoing 30 min of ventricular fibrillation and cardiopulmonary resuscitation (CPR)
Design
Preclinical
Authors
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Supports targeting aortic diastolic pressure in prolonged VF animal models; leaves open translation to human CPR.
Does maintaining aortic diastolic blood pressure above 30 mm Hg with epinephrine and saline improve successful resuscitation in a canine model of prolonged ventricular fibrillation?
Maintaining adequate aortic diastolic blood pressure during CPR is associated with successful resuscitation from prolonged ventricular fibrillation in a canine model.
Sanders et al. (1984) studied this question.