A binary star is born. Two unmodified DNA strands were found to form a catalytically active core upon hybridization to abutting positions of a DNA analyte (see figure). The DNAzyme cleaved a fluorophore- and quencher-labeled substrate; this resulted in increased fluorescence of the solution.
No takes yet. Share an insight, caveat, or question.
Dmitry M. Kolpashchikov (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: