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September 1, 2015Transplantation

Indoleamine 2, 3-Dioxgenase Transfected Mesenchymal Stem Cells Induce Kidney Allograft Tolerance by Increasing the Production and Function of Regulatory T Cells

Yue He Shan Zhou Hong Liu Bingbing Shen Hongwen Zhao Peng Kanfu Xiongfei Wu

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Abstract

The IDO increased the direct immunoregulatory properties of MSCs. The IDO-MSCs enhanced the expression and function of CD4CD25 Foxp3 Treg cells and induced allograft tolerance.

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He et al. (2015) studied this question.

synapsesocial.com/papers/69dd62397808b00a4799d737 https://doi.org/10.1097/tp.0000000000000856

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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