Anesthesia-Related Outcomes for Endovascular Stroke Revascularization
Why the study?
Does general anesthesia worsen outcomes compared to conscious sedation/local anesthesia in acute ischemic stroke patients undergoing intra-arterial therapy?
Population
Acute ischemic stroke patients undergoing intra-arterial therapy
Comparison
General anesthesia (GA) vs Conscious sedation/local anesthesia
Design
Review
Authors
Discussion
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Member takes
Implication
May warrant preferring conscious sedation for endovascular thrombectomy; leaves open confirmation by randomized trials.
Structured PICO
Does general anesthesia worsen outcomes compared to conscious sedation/local anesthesia in acute ischemic stroke patients undergoing intra-arterial therapy?
P
Population
Acute ischemic stroke patients undergoing intra-arterial therapy
I
Intervention
General anesthesia (GA)
C
Comparator
Conscious sedation/local anesthesia
O
Outcome
Clinical outcomes
Current evidence suggests general anesthesia may worsen outcomes in acute ischemic stroke patients undergoing intra-arterial therapy compared to conscious sedation, but adequately powered RCTs are needed.
Limitations
- retrospective studies
- selection bias
Cite This Study
Brinjikji et al. (2017) studied this question.