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April 14, 2021Genome MedicineOpen Access

PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

Bing Yao Tao Gui Xiangwei Zeng Yexuan Deng Zhi Wang Ying Wang Dongjun Yang Qi‐Xiang Li Peipei Xu Ruifeng Hu Xinyu Li Bing Chen Jin Wang Ke Zen Haitao Li Melissa J. Davis Marco J. Herold Huafeng Pan Zhiwei Jiang David C.S. Huang Ming Liu Junyi Ju Quan Zhao

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Abstract

PRMT1-mediated H4R3me2a recruits SMARCA4, which promotes colorectal cancer progression by enhancing EGFR signaling.

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Cite This Study

Yao et al. (2021) studied this question.

synapsesocial.com/papers/69dd68ebc5e71f791810112b https://doi.org/10.1186/s13073-021-00871-5

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Global patterns and trends in colorectal cancer incidence and mortalityOriginal Research · 2016 · 5,235 citations
2Epigenetic modifications of histones in cancerReview · 2019 · 552 citations
3Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid LeukemiaOriginal Research · 2016 · 184 citations
4PRMT1 Is a Novel Regulator of Epithelial-Mesenchymal-Transition in Non-small Cell Lung CancerOriginal Research · 2015 · 150 citations
5Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancersOriginal Research · 2010 · 314 citations

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