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June 20, 2019SHILAP Revista de lepidopterologíaOpen Access

Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

Ignácio Aguilar Andrés Legarra F. F. Cardoso Yutaka Masuda Daniela Lourenço I. Misztal

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Abstract

The use of a p-value for SSGWAS is a very general and efficient strategy to identify quantitative trait loci (QTL). It can be used for complex datasets such as those used in animal breeding, where only a proportion of the pedigreed animals are genotyped.

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Aguilar et al. (2019) studied this question.

synapsesocial.com/papers/69dd693880eea7d3f699cb9b https://doi.org/10.1186/s12711-019-0469-3

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Estimation of effects of single genes on quantitative traitsOriginal Research · 1992 · 226 citations
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