Indoleamine 2,3-dioxygenase 1 expression predicts cholangiocarcinoma patient survival

Mallika Naeklang; Hasaya Dokduang; Piya Prajumwongs; Poramate Klanrit; Arporn Wangwiwatsin; Nisana Namwat; Attapol Titapun; Prakasit Sa-Ngiamwibool; Watcharin Loilome

doi:10.1016/j.yexmp.2026.105042

April 10, 2026Experimental and Molecular PathologyOpen Access

Indoleamine 2,3-dioxygenase 1 expression predicts cholangiocarcinoma patient survival

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Key Points

The aim is to evaluate the prognostic significance of ido1 expression in cholangiocarcinoma patients.
Analyzed ido1 expression levels in cholangiocarcinoma tissue samples.
Correlated ido1 levels with patient survival metrics.
Used statistical methods to assess the independence of ido1 as a prognostic factor.
High ido1 expression was associated with significantly lower survival rates.
ido1 expression was identified as an independent prognostic factor.
Results suggest that ido1 could inform treatment planning for cholangiocarcinoma patients.

Implication

High ido1 expression predicts poorer outcomes in cholangiocarcinoma, suggesting its role as a prognostic biomarker.

Abstract

This finding indicates that high IDO1 expression is an independent prognostic factor linked to poorer patient outcomes, suggesting its potential as a biomarker for prognosis and treatment planning in CCA.

Discussion

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Cite This Study

Naeklang et al. (2026) studied this question.

synapsesocial.com/papers/69ddd8eee195c95cdefd666d https://doi.org/10.1016/j.yexmp.2026.105042

View Full Paper

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Indoleamine 2,3-dioxygenase 1 expression predicts cholangiocarcinoma patient survival

Key Points

Implication

Abstract

Discussion

Cite This Study

Indoleamine 2,3-dioxygenase 1 expression predicts cholangiocarcinoma patient survival

Key Points

Implication

Abstract

Discussion

Cite This Study

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