The human placental ex vivo vessel perfusion method could be used to assess human MSC migration into human tissue. Cells of the MSC lines were able to adhere and transmigrate through the endothelial barrier in a manner similar to that of leukocytes. Notably, cells that transmigrated remained in close proximity to the endothelium, which is consistent with the reported MSC vascular niche in placental blood vessels.
No takes yet. Share an insight, caveat, or question.
Al-Sowayan et al. (2019) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: