March 10, 2019Alimentary Pharmacology & Therapeutics26 citationsOpen Access

Relationship between resolution of non‐alcoholic steatohepatitis and changes in lipoprotein sub‐fractions: a post‐hoc analysis of the PIVENS trial

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KCKathleen E. Corey LWLaura Wilson AAAkif Altınbaş

Structured PICO

Is resolution of NASH associated with favorable changes in serum lipoprotein sub-fractions?

Population

Patients with non-alcoholic steatohepatitis (NASH) from the PIVENS trial

Intervention

Resolution of NASH

Comparator

Non-resolution of NASH

Outcome

Changes in serum lipoprotein sub-fractionssurrogate

Resolution of NASH is associated with favorable changes in serum lipoprotein levels, suggesting a potential mechanism for cardiovascular risk reduction.

Abstract

NASH resolution is associated with favourable changes in a subset of serum lipoprotein levels. More studies are warranted to understand if these favourable changes are associated with decreased risk of CVD.

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Relationship between resolution of non‐alcoholic steatohepatitis and changes in lipoprotein sub‐fractions: a post‐hoc analysis of the PIVENS trial

Structured PICO

Abstract

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