Why the study?
Does diet-induced weight loss affect circulating levels of miR-122-5p, miR-126a-3p, miR-193a-5p, and miR-222-3p?
Does diet-induced weight loss affect circulating levels of miR-122-5p, miR-126a-3p, miR-193a-5p, and miR-222-3p?
Circulating miR-122-5p may serve as a biomarker for adverse metabolic health independent of obesity and responds to diet-induced weight loss.
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miR-122-5p may track adverse metabolic health independent of obesity after weight loss; extends biomarker research with RCT data.
Changes in circulating miR-122-5p, miR-126a-3p, miR-193a-5p, and miR-222-3p in response to diet-induced weight loss are demonstrated. Furthermore, assessment of miR-122-5p could be an indicator of an adverse metabolic health status independent of obesity.
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Hess et al. (2020) studied this question.
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