Why the study?
Does catheter ablation of specific left atrial structures improve termination of long-lasting persistent atrial fibrillation?
Does catheter ablation of specific left atrial structures improve termination of long-lasting persistent atrial fibrillation?
Ablation of the left atrial appendage, coronary sinus, and pulmonary veins plays a critical role in terminating long-lasting persistent atrial fibrillation.
Should not yet change ablation practice in persistent AF; leaves open the efficacy of targeting specific left atrial sites in prospective trials.
Termination of persistent AF can be achieved in 87% of patients by catheter ablation. Ablation of the structures annexed to the left atrium-the left atrial appendage, coronary sinus, and PVs-have the greatest impact on the prolongation of AF cycle length, the conversion of AF to atrial tachycardia, and the termination of focal atrial tachycardias.
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Haı̈ssaguerre et al. (2005) studied this question.
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