Why the study?
Does BNP inhibit TGF-beta-induced profibrotic effects in primary human cardiac fibroblasts?
Does BNP inhibit TGF-beta-induced profibrotic effects in primary human cardiac fibroblasts?
BNP exerts broad functional opposition to TGF-beta in primary human cardiac fibroblasts, suggesting an antifibrotic role to prevent cardiac remodeling.
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Does not support clinical adoption; hypothesis-generating for BNP's antifibrotic effects in cardiac fibroblasts.
Kapoun et al. (2004) studied this question.
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