Why the study?
Does excessive polypharmacy predict changes in nutritional status, functional ability, and cognitive capacity over a three-year period in an elderly population?
Does excessive polypharmacy predict changes in nutritional status, functional ability, and cognitive capacity over a three-year period in an elderly population?
While excessive polypharmacy is associated with worse nutritional, functional, and cognitive status in the elderly, it does not predict the trajectory of decline over a three-year period.
Excessive polypharmacy signals higher risk without predicting three-year decline; leaves open whether deprescribing alters trajectories in elderly cohorts.
Excessive polypharmacy is associated with decline in nutritional status, functional ability and cognitive capacity in elderly persons. However, the changes in nutrition, physical functionality and cognition over a three-year period cannot be predicted by polypharmacy status.
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Jyrkkä et al. (2011) studied this question.
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