Why the study?
Is intraoperative hypotension associated with postoperative acute kidney injury in patients undergoing elective noncardiac surgery?
Is intraoperative hypotension associated with postoperative acute kidney injury in patients undergoing elective noncardiac surgery?
Sustained intraoperative hypotension (MAP < 55 or < 60 mmHg) is associated with an increased risk of postoperative acute kidney injury in elective noncardiac surgery.
Highlights AKI risk with sustained MAP <55-60 mmHg in noncardiac surgery; hypothesis-generating and requires prospective trials.
In this analysis, postoperative AKI is associated with sustained intraoperative periods of MAP less than 55 and less than 60 mmHg. This study provides an impetus for clinical trials to determine whether interventions that promptly treat IOH and are tailored to individual patient physiology could help reduce the risk of AKI.
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Sun et al. (2015) studied this question.
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