Why the study?
Does intravenous dexmedetomidine reduce postoperative pain and opioid consumption in adults undergoing surgery?
Population
28 RCTs pooling 1420 adult patients undergoing surgery
Comparison
Intravenous administration of dexmedetomidine… vs Placebo or opioids
Design
Meta-analysis
Follow-up
up to 24 hours postoperatively
Authors
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Supports intraoperative dexmedetomidine to reduce early postoperative pain and opioid consumption; confirms efficacy while cautioning on bradycardia risk.
Does intravenous dexmedetomidine reduce postoperative pain and opioid consumption in adults undergoing surgery?
Intraoperative dexmedetomidine reduces postoperative pain and opioid consumption but increases the risk of intraoperative bradycardia.
Schnabel et al. (2013) studied this question.
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