Why the study?
Does single-stage combined TAVI and PCI provide comparable survival and safety to TAVI alone in patients with severe aortic stenosis?
Does single-stage combined TAVI and PCI provide comparable survival and safety to TAVI alone in patients with severe aortic stenosis?
Single-stage combined TAVI and PCI for severe aortic stenosis and CAD is safe and feasible, with survival up to 3 years comparable to TAVI alone in patients without CAD, without an increased risk of acute kidney injury.
Answers are grounded in this paper and cite their sources.
Supports combined TAVI-PCI feasibility without excess AKI; hypothesis-generating and requires randomized confirmation before practice change.
Single-stage combined treatment of severe aortic stenosis and highly relevant coronary lesions is a safe and feasible procedure. Early survival and survival up to 3 years are comparable to that observed in patients presenting without CAD who received TAVI only. PCI effectively reduces the complexity of coronary lesions. Although more contrast agent is applied during the combined treatment, the rate of acute kidney injury was not higher.
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Penkalla et al. (2014) studied this question.
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