Why the study?
Does acute hyperglycemia cause endothelial dysfunction in healthy and cardiometabolic diseased subjects?
Does acute hyperglycemia cause endothelial dysfunction in healthy and cardiometabolic diseased subjects?
Acute hyperglycemia acutely impairs macrovascular, but not microvascular, endothelial function in both healthy individuals and those with cardiometabolic disease.
Acute hyperglycemia impairs macrovascular endothelial function; confirms selective macro- versus microvascular effects in healthy and cardiometabolic subjects.
To our knowledge, this is the first systematic review and meta-analysis of its kind. In healthy and diseased subjects, we found evidence for macrovascular but not microvascular endothelial dysfunction during acute hyperglycemia.
No takes yet. Share an insight, caveat, or question.
Loader et al. (2015) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: