Key result
T1DM is linked to higher AMI and HF hospitalization risk even with risk factors at target.
Why the study?
A steep-graded association between decreasing number of cardiovascular risk factors at target and major adverse cardiovascular outcomes among patients with T1DM was observed, but risks remained higher compared with controls even when all risk factors were at target.
Does achieving target levels for cardiovascular risk factors eliminate the excess risk of major adverse cardiovascular outcomes in patients with T1DM compared to controls?
Observational
Does achieving target levels for cardiovascular risk factors eliminate the excess risk of major adverse cardiovascular outcomes in patients with T1DM compared to controls?
Patients with T1DM remain at a significantly higher risk for acute myocardial infarction and heart failure hospitalization compared to controls, even when all cardiovascular risk factors are optimally controlled.
Persistent excess AMI and HF risk in T1DM persists even at target levels; leaves open whether T1DM-specific strategies are required.
A steep-graded association exists between decreasing number of cardiovascular risk factors at target and major adverse cardiovascular outcomes among patients with T1DM. However, risks for all outcomes were numerically higher for patients with T1DM compared with controls, even when all risk factors were at target, with risk for acute myocardial infarction and heart failure hospitalization statistically significantly higher.
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Rawshani et al. (2017) conducted an observational in Type 1 Diabetes Mellitus (T1DM). Type 1 Diabetes Mellitus vs. Controls was evaluated on Major adverse cardiovascular outcomes, acute myocardial infarction, and heart failure hospitalization. Patients with T1DM had a statistically significantly higher risk for acute myocardial infarction and heart failure hospitalization compared with controls, even when all risk factors were at target.
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