Population
Embryonic human hearts between the 4th and 8th week of development
Design
Preclinical
Authors
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Animal data on MHC isoform patterns require human validation before any clinical use; leaves open translational relevance to congenital heart disease.
The study maps the spatial distribution of alpha- and beta-myosin heavy chain isoforms in the developing human heart, highlighting specific expression patterns related to cardiac structures and the conduction system.
Wessels et al. (1991) studied this question.
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