Population
Human HeLa (carcinoma) and U937 (promonocytic) cell lines infected with poliovirus
Design
Preclinical
Authors
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Exogenous NO donation may prolong poliovirus infection; leaves open whether NO modulation affects viral clearance.
Exogenous nitric oxide donation via glycerine trinitrate can lengthen the course of poliovirus infection in human cell lines, whereas endogenous NO production is insufficient to limit viral productivity.
López‐Guerrero et al. (1998) studied this question.
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