Population
Human monocytic cell line U-937 and erythroleukemic cell line K-562
Design
Preclinical
Authors
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Suggests monocyte-specific restriction of poliovirus; leaves open relevance to cardiac viral tropism or myocarditis models.
Human monocytic U-937 cells exhibit a discriminatory mechanism that restricts poliovirus RNA translation despite successful infection and mRNA accumulation.
López‐Guerrero et al. (1989) studied this question.
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