Proper interpretation of kidney function and cardio-renal interactions is crucial in heart failure to ensure adequate decongestion and optimal dosing of guideline-directed medical therapy.
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Avoid misinterpreting worsening renal function to prevent inadequate decongestion and GDMT underdosing in HF; reinforces integrated cardio-renal assessment in guidelines and trials.
Müllens et al. (2020) studied this question.