June 4, 2007Advanced Synthesis & Catalysis
Enzyme Immobilization: The Quest for Optimum Performance
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Implication
Review reveals methods to optimize biocatalyst stability in industrial media, highlighting novel supports and cross-linking strategies.
Key Points
- To review and classify enzyme immobilization methodologies to identify strategies that optimize catalytic performance and stability in industrial systems.
- Classified enzyme immobilization techniques into carrier binding, polymer entrapment, and enzyme cross-linking.
- Synthesized recent developments in advanced supports, including mesoporous silicas, hydrogels, smart polymers, and cross-linked enzyme aggregates (CLEAs).
- Categorized immobilization into binding to prefabricated carriers, entrapping within polymer matrices, and cross-linking enzyme molecules.
- Identified cross-linked enzyme aggregates and novel supports like mesoporous silicas as primary tools to improve operational stability in non-aqueous industrial media.
Cite This Study
Roger A. Sheldon (2007) studied this question.