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January 1, 2018Cellular Physiology and Biochemistry71 citationsOpen Access

Qiliqiangxin Attenuates Cardiac Remodeling via Inhibition of TGF-β1/Smad3 and NF-κB Signaling Pathways in a Rat Model of Myocardial Infarction

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AHAnbang HanJining First People's HospitalYLYingdong LuNanotherapeutics (United States)QZQi ZhengChinese Academy of Medical Sciences & Peking Union Medical College

Structured PICO

Does Qiliqiangxin therapy attenuate cardiac remodeling in a rat model of myocardial infarction?

P
Population
Rat model of myocardial infarction
I
Intervention
Qiliqiangxin (QL) therapy
O
Outcome
Cardiac remodeling, cardiac function, myocardial inflammation, and fibrosissurrogate

Qiliqiangxin therapy attenuates cardiac remodeling, preserves cardiac function, and reduces inflammation and fibrosis in a rat model of myocardial infarction.

Abstract

QL therapy exerted protective effects against cardiac remodeling potentially by inhibiting TGF-β1/Smad3 and NF-κB signaling pathways, thereby preserving cardiac function, as well as reducing myocardial inflammation and fibrosis.

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Cite This Study

Han et al. (2018) studied this question.

synapsesocial.com/papers/69dec5c5fd84e72eb2558c0ahttps://doi.org/10.1159/000487871
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