Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

A. John Rush; Madhukar H. Trivedi; Jonathan W. Stewart; Andrew A. Nierenberg; Maurizio Fava; Benji T. Kurian; Diane Warden; David W. Morris; James F. Luther; Mustafa M. Husain; Ian A. Cook; Richard C. Shelton; Ira M. Lesser; Susan G. Kornstein; Stephen R. Wisniewski

doi:10.1176/appi.ajp.2011.10111645

May 2, 2011American Journal of Psychiatry

Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

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Neither medication combination outperformed monotherapy. The combination of extended-release venlafaxine plus mirtazapine may have a greater risk of adverse events.

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Rush et al. (2011) studied this question.

synapsesocial.com/papers/69dee38a92a5e9426ae93c13 https://doi.org/10.1176/appi.ajp.2011.10111645

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Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

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Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

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