Does enoxaparin dosage adjusted by anti-Factor Xa trough level reduce clinically evident venous thromboembolism in trauma patients?
Adjusting enoxaparin dosage based on anti-Xa trough levels may reduce VTE risk in trauma patients without increasing bleeding.
In this study, subprophylactic anti-Xa trough levels were common in trauma patients. Enoxaparin dosage adjustment may lead to a reduced rate of VTE without an increased risk of bleeding.
Ko et al. (Wed,) studied this question.