Does the choice between nifedipine, hydralazine, and labetalol affect efficacy and safety in treating severe hypertension in pregnancy?
Nifedipine, hydralazine, and labetalol show similar efficacy for treating severe hypertension in pregnancy, though safety profiles may differ slightly.
The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy. Subtle differences may exist in their safety profile. The evidence is inadequate for other drugs.
Sridharan et al. (Thu,) studied this question.