Why the study?
Does the presence of severe fixed stenosis increase the risk of myocardial infarction, sudden death, or arrhythmias in patients with vasospastic angina?
Population
349 patients with vasospastic angina followed in eight centers in Japan.
Design
Cohort
Follow-up
3.4 +/- 0.1 years (mean +/- SE)
Authors
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Severe fixed stenosis may identify higher MI risk in vasospastic angina; supports risk stratification but leaves causal inference and intervention effects open.
Does the presence of severe fixed stenosis increase the risk of myocardial infarction, sudden death, or arrhythmias in patients with vasospastic angina?
In Japanese patients with vasospastic angina treated with calcium blockers, cardiac events are infrequent, but the presence of severe fixed stenosis markedly increases the risk of myocardial infarction.
Nakamura et al. (1987) studied this question.