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Cohort study reveals high rates of major depressive disorder after traumatic brain injury, indicating severe impacts on health-related quality of life.
Among a cohort of patients hospitalized for TBI, 53.1% met criteria for MDD during the first year after TBI. Major depressive disorder was associated with history of MDD and was an independent predictor of poorer health-related quality of life.
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Charles H. Bombardier (2010) studied this question.
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